TOOLS Collagen I, Rat tail, Lyophilized
TOOLS provides Collagen I formulated in high purity, quality and ultra-low endotoxin, which sets the supreme standard in the industry. TOOLS Collagen I is an extraordinary matrix material for coating surface in 2D culture to promote cell adhesion, growth, differentiation, and migration of various cell types, such as hepatocytes, fibroblasts, spinal ganglion, muscle cells, Schwann cells, epithelial cells. And TOOLS Collagen I is ideal for establishing 3D culture where it mimics the animal ECM to allow the researchers to investigate the mechanical properties of the ECM on cell development, chemotaxis, migration, and morphology.
Feature
Workflow
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Supreme purity, about > 95% collagen by SDS-PAGE
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Sterility test following USP and low endotoxin (≤ 1.0 EU/ml by LAL assay)
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QC with Cell Attachment Assay every lot
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Promotes adhesion of various types of cells
Workflow
Improved cell attachment
Figure 1. Microglia cells (Mus musculus) are cultured in 2D on a coating surface using TOOLS collagen 1. Representative of positively stained microglia marker, Iba-1 showed TOOLS collagen 1 enhanced cell adhesion and structure.
Figure 2. PC12 cells are cultured in 2D on a coating surface using TOOLS collagen 1. Representative microphotographs showed TOOLS collagen 1 enhanced cell adhesion and proliferation.
Figure 3. PC12 cells are cultured in 2D on coating surface using TOOLS collagen I or collagen I product from well-known manufacturer, Competitor C, respectively. Representative microphotographs showed TOOLS collagen 1 enhanced cell adhesion and proliferation greater than Competitor C collagen I.