Metabolomics is a rapid growth omics in the past five years. Metabolomics refers to the identification and quantification of small molecular metabolic (MW<1500 Da) at a specific time in biological system (e.g. cell, tissue, biological fluid…etc.). Metabolic is the end product in the biological system, it refers to the status and the phenotype of an organism at a particular time more directly compared with gene or protein. Metabolomics has many applications, including clinical diagnostics, changes of the metabolites under different environments or conditions of plants or other animals…etc.